Northwestern hasn't played a game with Chris Collins as a head coach yet, but he's clearly challenged the normally low expectations. It's not going to happen quickly, and given the inertia that has existed there, there's obviously a chance of failure as well.
But if anyone can do it, it's Collins. He's a native, he has intimate knowledge of the university and just as importantly, how to deal with a demanding admissions department. The biggest question is getting the players. If he can't get top-flight talent, he could still have a more modest success. But would anyone really bet against him with quality players?